Detalhe da pesquisa
1.
Mechanism of gating and partial agonist action in the glycine receptor.
Cell
; 184(4): 957-968.e21, 2021 02 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33567265
2.
Acidic pH reduces agonist efficacy and responses to synaptic-like glycine applications in zebrafish α1 and rat α1ß recombinant glycine receptors.
J Physiol
; 600(2): 333-347, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34802146
3.
The intracellular domain of homomeric glycine receptors modulates agonist efficacy.
J Biol Chem
; 296: 100387, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33617876
4.
Heterogeneity of cell membrane structure studied by single molecule tracking.
Faraday Discuss
; 232(0): 358-374, 2021 12 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34647559
5.
The startle disease mutation α1S270T predicts shortening of glycinergic synaptic currents.
J Physiol
; 598(16): 3417-3438, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32445491
6.
The Startle Disease Mutation E103K Impairs Activation of Human Homomeric α1 Glycine Receptors by Disrupting an Intersubunit Salt Bridge across the Agonist Binding Site.
J Biol Chem
; 292(12): 5031-5042, 2017 03 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28174298
7.
Bayesian Statistical Inference in Ion-Channel Models with Exact Missed Event Correction.
Biophys J
; 111(2): 333-348, 2016 Jul 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-27463136
8.
Altered development in GABA co-release shapes glycinergic synaptic currents in cultured spinal slices of the SOD1(G93A) mouse model of amyotrophic lateral sclerosis.
J Physiol
; 594(13): 3827-40, 2016 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27098371
9.
Inhibition of the prokaryotic pentameric ligand-gated ion channel ELIC by divalent cations.
PLoS Biol
; 10(11): e1001429, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23185134
10.
Agonist and antagonist binding in human glycine receptors.
Biochemistry
; 53(38): 6041-51, 2014 Sep 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-25184435
11.
On the nature of partial agonism in the nicotinic receptor superfamily.
Nature
; 454(7205): 722-7, 2008 Aug 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-18633353
12.
The α1K276E startle disease mutation reveals multiple intermediate states in the gating of glycine receptors.
J Neurosci
; 32(4): 1336-52, 2012 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-22279218
13.
The kinetic properties of the α3 rat glycine receptor make it suitable for mediating fast synaptic inhibition.
J Physiol
; 591(13): 3289-308, 2013 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23613537
14.
Chloride ions in the pore of glycine and GABA channels shape the time course and voltage dependence of agonist currents.
J Neurosci
; 31(40): 14095-106, 2011 Oct 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-21976494
15.
In glycine and GABA(A) channels, different subunits contribute asymmetrically to channel conductance via residues in the extracellular domain.
J Biol Chem
; 286(15): 13414-22, 2011 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21343294
16.
Aminomethanesulfonic acid illuminates the boundary between full and partial agonists of the pentameric glycine receptor.
Elife
; 112022 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35975975
17.
THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Ion channels.
Br J Pharmacol
; 178 Suppl 1: S157-S245, 2021 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-34529831
18.
Intracellular chloride ions regulate the time course of GABA-mediated inhibitory synaptic transmission.
J Neurosci
; 29(33): 10416-23, 2009 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-19692617
19.
What single-channel analysis tells us of the activation mechanism of ligand-gated channels: the case of the glycine receptor.
J Physiol
; 588(Pt 1): 45-58, 2010 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19770192
20.
High intracellular chloride slows the decay of glycinergic currents.
J Neurosci
; 28(45): 11454-67, 2008 Nov 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-18987182